ea0015p276 | Reproduction | SFEBES2008
Asby Daniel
, Wood Peter
, Hanley Neil
Mammalian differentiation of the external genitalia must be strictly dimorphic for reproductive success. In humans, this is established by a complex interplay of genetic and hormonal factors during 712 weeks post-conception (wpc). Despite being fundamental to normal human biology, understanding of human sexual differentiation remains limited. Our objective was to define the onset and regulation of androgen biosynthesis in the human fetal testis and correlate this to diff...